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Preclinical: Laboratory & animal models Goal: Explore if & how new treatment may work Phase I: Small number (eg, 20-100) of healthy subjects Goal: Evaluate toxicity, maximum tolerated dose, adverse effects, pharmacokinetics & pharmacodynamics of new treatment (safety) Phase II: Small number (eg, up to a few hundred) of affected subjects Goal ...
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Removing a cast too early can undo weeks of healing. It keeps the bone aligned, protects it from impact, and gives new tissue time to grow strong again. Even if it feels better, the bone underneath is still fragile, patience really matters in recovery. What are your thoughts? VC: @morgan_asbill Follow @doctorsoood to improve your health IQ and for similar content. #orthopedics #fracture #bonehealing #pediatrics #medicaleducation
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