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Lupus Science & Medicine® is a global, peer reviewed, open access online journal that provides a central point for publication of basic, clinical, translational, and epidemiological studies of all …
5-Hydroxymethylcytosine in circulating cell-free DNA as a …
Background SLE is a complex autoimmune disease with heterogeneous manifestations and unpredictable outcomes. Early diagnosis is challenging due to non-specific symptoms, and …
The SRI- 4 was developed in response to the need for a robust primary outcome measure for clinical trials, stem-ming from a post hoc analysis of the unsuccessful beli-mumab phase II …
SARS-CoV-2 spike aggravates lupus nephritis and lung fibrosis in ...
Objective COVID-19 induces the development of autoimmune diseases, including SLE, which are characterised by inflammation, autoantibodies and thrombosis. However, the effects of COVID …
Major infections in newly diagnosed systemic lupus …
Objective To evaluate the risk of major infections and the relationship between major infections and mortality in patients with newly diagnosed SLE. Methods A newly diagnosed (<3 months) …
Utility of skin biopsy in patients with systemic lupus erythematosus ...
Systemic lupus erythematosus (SLE) is a systemic autoimmune disease that can affect multiple organs, commonly the skin in 70%–85% of patients.1 Cutaneous lupus is associated with the …
PO.6.127 Efavaleukin alfa, a novel IL-2 mutein, selectively expands ...
Purpose Defects in regulatory T cell (Treg) number and function are associated with autoimmune diseases including SLE. Interleukin (IL)-2 is essential for the development and suppressive …
quality of life are relevant for SLE patients.Among the possible non-pharmacological interventions,2 exercise and diet have a pivotal role.1 For SLE patients aerobic exercise …
Cutaneous vasculitis in SLE | Lupus Science & Medicine
Cutaneous vasculitis was observed in 17.3% of patients with SLE. The mean time to cutaneous vasculitis after SLE diagnosis was 4.78 years (95% CI 3.96 to 5.60). Among patients who …
Validating claims-based algorithms for a systemic lupus …
Objective This study aimed to validate claims-based algorithms for identifying SLE and lupus nephritis (LN) in Medicare data, enhancing the use of the Lupus Index for geospatial research …