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  1. 340B Drug Pricing Program | HRSA

    Learn about HRSA's Office of Pharmacy Affairs (OPA), ensuring affordable medications through the 340B Drug Pricing Program.

  2. 340B Rebate Model Pilot Program | HRSA

    The 340B Rebate Model Pilot Program consists of a selected group of drugs of manufacturers who have submitted plans meeting specific criteria that HRSA has approved.

  3. 340B Eligibility | HRSA

    Discover eligibility and registration details for HRSA's 340B Drug Pricing Program to help entities access discounted medications

  4. 340B Educational Resources | HRSA

    Our website provides resources to help 340B Program stakeholders with navigating the 340B Program, including registration and implementation, requirements compliance, program …

  5. FAQs | HRSA

    Which manufacturers and drugs are subject to 340B pricing, and can participating manufacturers offer only a subset of the drugs they manufacture at 340B prices?

  6. Welcome to 340B OPAIS

    Dec 25, 2025 · Have questions? Contact the 340B Prime Vendor www.340bpvp.com 1-888-340-2787 8AM-5PM CT Mon-Fri [email protected]

  7. Program Requirements | HRSA

    To purchase drugs at the 340B price, covered entities must continue to meet the requirements of the 340B Drug Pricing Program.

  8. 340B Office of Pharmacy Affairs Information System | HRSA

    The 340B registration and pricing databases are known as the 340B Office of Pharmacy Affairs Information System (340B OPAIS). Authorized users of 340B OPAIS must have a user …

  9. 340B Registration

    Participation in the 340B Program allows nonprofit healthcare organizations to receive outpatient drugs at significantly reduced prices. In order to participate in the 340B drug pricing program, …

  10. Getting Started - Health Resources and Services Administration

    The 340B OPAIS pricing module is the sole official federal source for 340B ceiling prices; it calculates those prices based on information supplied by pharmaceutical manufacturers, the …