Background Anti-C1q autoantibodies can disrupt normal complement function, contributing to the formation of pathogenic immune ...

Background Lupus nephritis (LN) is the most serious complication of SLE. Interstitial fibrosis is the dominant pathological ...

Objective Peer mentoring has been shown to be an effective intervention for chronic conditions with evidence to suggest that ...

Objective Small fibre neuropathy (SFN) is an under-recognised complication of SLE that contributes to chronic pain and ...

Glucocorticoids represent the most potent class of anti-inflammatory drugs. However, their anti-inflammatory mode of action has been incompletely understood. Recent insights have revealed a key role ...

Objective To evaluate the effect of early belimumab administration on disease progression in patients with early active SLE. Methods This multicentre observational study included patients with early ...

Background Social determinants of health (SDoH) contribute to inequities in rheumatic disease care and outcomes especially among individuals with rheumatoid arthritis (RA) and systemic lupus ...

Objective Macrophage activation syndrome (MAS), a subtype of secondary haemophagocytic lymphohistiocytosis (HLH), is a rare ...

Malignancy risk in systemic lupus erythematosus (SLE) is about 15% higher than the general age-and-sex-matched population. Hematologic cancers, especially B-cell lymphomas, are about three-fold ...