A deadly wrong-way crash on the southbound 405 Freeway in Sherman Oaks has prompted the closure of all lanes early Tuesday.

The California Highway Patrol has closed all lanes of the southbound 405 Freeway in Encino after a deadly crash.

All lanes of the southbound 405 Freeway in Encino are blocked after a deadly crash left one person dead Tuesday morning. The ...

At least one person is dead following a wrong-way crash on the southbound lanes of the 405 Freeway in Sherman Oaks.

At least one person was killed in a reported wrong-way crash on the 405 Freeway in Encino, prompting the closure of all ...

All southbound lanes of the 405 Freeway were shut down in the Encino area following a crash involving several cars Tuesday morning.