Hackensack Meridian John Theurer Cancer Center Unveils Research at the 67th American Society of Hematology Annual Meeting

Investigators from Hackensack Meridian John Theurer Cancer Center (JTCC)—a leading research partner of the NCI-designated ...
sicklecellanemianews

Trial launched to test DISC-3405 for easing iron overload in SCD

Disc Medicine has launched a small clinical trial to test DISC-3405, its treatment candidate for reducing iron levels and easing iron overload, in people with sickle cell disease (SCD). The Phase 1b ...
TMCnet

ORYZON Announces First-Patient-In (FPI) in RESTORE Phase Ib Trial of Iadademstat in Sickle Cell Disease

Recently approved by the European Medicines Agency, RESTORE will evaluate iadademstat’s ability to raise fetal hemoglobin (HbF) in adult patients with SCD Iadademstat has demonstrated a favorable ...
ahajournals.org

Abstract 4368394: Comprehensive Phenotypic Characterization of Late Gadolinium Enhancement Improves Sudden Cardiac Death Risk Stratification in Nonischemic Dilated Cardiomyopathy

Background: Late gadolinium enhancement (LGE) is an established predictor of sudden cardiac death (SCD) in nonischemic dilated cardiomyopathy (DCM). However, the prognostic value of LGE ...
ahajournals.org

Abstract 4368062: Subendocardium-involved Late Gadolinium Enhancement Pattern with Noncoronary Distribution Predicts Sudden Cardiac Death in Nonischemic Dilated Cardiomyopathy

Background: Beyond the predominant nonischemic late gadolinium enhancement (LGE) pattern, an subendocardium-involved LGE patternwas also identified in a subset of patients with nonischemic dilated ...