PI3K inhibitors: decades of partnership between ICR researchers and industry leads to a new class of cancer drugs We share the story of a pioneering and collaborative research programme at the ICR, ...

Despite much interest in vascular endothelial growth factor (VEGF) and its receptors (VEGFRs -1 and -2), VEGF-induced signalling cascades remain incompletely defined. Attempts to assign individual ...

Novartis published trial results showing its drug succeeded in tackling difficult to treat breast cancer with PIK3CA mutation, after other pharma giants including Roche failed and abandoned ...

If the deal goes through, Scorpion will spin its non-PI3K pipeline assets – which include a pair of EGFR inhibitors codenamed STX-721 and STX-241 – into a new, as-yet-unnamed independent ...

Food Services provide the Concordia community with fresh, healthy, delicious and accessible choices through sustainable practices. Learn more about where to eat, meal plan options and catering ...

Review Article Published: March 1999 Hepatocyte growth factor, a versatile signal for developing neurons Flavio Maina & Rüdiger Klein Nature Neuroscience 2, 213–217 (1999) Cite this article ...

Protein kinase inhibitors with an allosteric mode of action are expected to reach, in many cases, higher selectivity for the target enzyme than ATP-competitive compounds. Therefore, basic research is ...