Loss of the Y chromosome in aging men is widespread and increasingly linked to serious diseases, challenging assumptions that the Y has little biological importance beyond sex determination.

Researchers screened more than 220,000 single-letter DNA changes, identifying thousands that regulate gene activity in brain, ...

Rapidly testing hundreds of thousands of DNA sequences, scientists identified specific genetic variations contributing to blood pressure, cholesterol, and blood sugar.

A massive genomics effort has identified thousands of single nucleotide non-coding variants, which alter gene activity, that link to disease and health.

Scientists have identified how specific genetic changes function in cells to influence disease risk and other human health ...

Scientists have identified how specific genetic changes function in cells to influence disease risk and other human health traits. By probing regions ...

Research in Aging Cell indicates that blood levels of particular small non-coding RNAs, which regulate gene expression, may ...

Research in Aging Cell indicates that blood levels of particular small non-coding RNAs, which regulate gene expression, may influence how long a ...

New techniques to detect Y chromosome genes show frequent loss of the Y in tissues of older men. The increase with age is ...

As millions of ageing men lose the Y chromosome, evidence links this silent shift to heart disease, cancer and shorter lives – what’s at stake?

Genetic studies now identify millions of variants across human populations, yet most disease-associated signals fall outside protein-coding regions. This ...