For gene therapy to work well, therapeutic molecules need to be efficiently delivered to the correct locations in the body—a ...

To understand the mechanism of the nasal vaccines, the researchers first injected mice with a traditional mRNA COVID-19 shot, ...

The nasal route offers a number of benefits over some of the traditional routes of administration for biologics.

Scientists have engineered a monoclonal antibody that can protect mice from a lethal dose of influenza A, a new study shows.

Instead of injecting it into the bloodstream, researchers turned it into a nasal spray. This strategy allowed the antibody to stick to the mucus lining of the nose and lungs, where flu viruses ...

Most vaccines — and boosters — are injected directly into muscle tissue, usually in the upper arm, to kickstart the body's immune system in the fight against disease.

An alternative, nasal spray, formulation has been developed that demonstrates good efficacy, high tolerability and a very fast onset of action. This study assessed the pharmacokinetics and ...

US researchers have engineered a novel gene therapy to target the airway and lungs via a nasal spray. For gene therapy to ...