We measured lipopolysaccharide (LPS), LPS-binding protein (LBP), intestinal fatty acid binding protein (I-FABP), and soluble cluster of differentiation 14 (sCD14) as markers of gut barrier dysfunction ...

Results Individuals with wheat sensitivity had significantly increased serum levels of soluble CD14 and lipopolysaccharide (LPS)-binding protein, as well as antibody reactivity to bacterial LPS and ...

LPS binds to TLR4, activates the MyD88-IRAK-TRAF6 pathway, and induces IKKβ activity within the IKK2 complex. Likewise, by binding IL-1R ... LPS causes upregulation and activation of apoptotic ...

From growth hormones to cancer drugs, small molecules play a crucial role in our health. Monitoring them is essential to ...

Mammalian genomes are organized by multi-level folding, yet how this organization contributes to cell type-specific transcription remain unclear. We uncovered that the nuclear protein SATB1 ...

Vitamin D (VD) binds to its receptor in the cytoplasm and ... Arrow: Facilitation; Cross tick: Inhibition.LPS: Lipopolysaccharide; VD: Vitamin D.

Creative Commons (CC): This is a Creative Commons license. Attribution (BY): Credit must be given to the creator. Sepsis presents a significant medical challenge due to its intense inflammatory ...

1 Department of Medicine, Division of Gastroenterology & Hepatology, University of Cambridge, Addenbrooke's Hospital, Cambridge, UK 2 Wellcome Trust PhD Programme for Clinicians, Cambridge Institute ...

DNA of gut microbiota can be found in synovium of osteoarthritis and rheumatoid arthritis. This finding could result from the translocation of still alive bacteria from gut to joints through blood, ...