A deadly wrong-way crash on the southbound 405 Freeway in Sherman Oaks has prompted the closure of all lanes early Tuesday.

A deadly wrong-way crash on the southbound 405 Freeway in Sherman Oaks shut down traffic on all lanes early Tuesday.

At least one person is dead following a wrong-way crash on the southbound lanes of the 405 Freeway in Sherman Oaks.

A deadly crash involving a wrong-way driver closed all southbound lanes of the 405 Freeway in Sherman Oaks heading into the ...

One person was killed and at least two others are in critical condition following a multi-vehicle collision involving a wrong-way driver that backed up traffic Tuesday for miles on the San Diego (405) ...

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