Transient Ca 2+ fluctuations on the surface of the endoplasmic reticulum (ER) can induce liquid-liquid phase separation (LLPS) of the autophagy initiation complex FIP200, forming FIP200 puncta and ...

For years, David Nutt, a neuropsychopharmacologist at Imperial College London and co-founder of GABA Labs, has been toying with the idea of a synthetic alcoholic drink that mimics the same ...

This is an important study using a combination of optogenetics and calcium imaging to provide insight into the function of the cholinergic input to the prelimbic cortex in probabilistic spatial ...

NMDAR function and CaMKII activation are required for these effects ... are known to block GABAergic responses due to its antagonistic effect on GABA-A receptors, thereby precluding the study of ...

CaMKII can also induce neuroprotective effects by activating the GABAA receptors (GABA A R) and extracellular signal–regulated kinase (ERK) as well as inhibiting neuronal nitric oxide synthase (nNOS) ...