Week 17 of "Monday Night Football" features the Detroit Lions and the San Francisco 49ers. Check out how to watch on ESPN.

The San Francisco 49ers return to Levi's Stadium to host the Detroit Lions on ESPN's Monday Night Football. This matchup ...

The San Francisco 49ers will hold three full practices this week as they gear up for their Week 17 Monday night matchup ...

What NFL teams can clinch a playoff spot? Here's the NFL playoff picture right now and NFL playoff clinching scenarios this ...

Here are the lines, spreads and totals for all 16 games on the Week 17 slate. Football Power Index (FPI) by ESPN Analytics.

SportsLine expert Eric Cohen reveals his score predictions for the 14 remaining games in Week 17 of the NFL schedule ...

Facing off the best secondary it has seen this season, the Lions' passing attack must be strong to hold onto the one seed.

The Green Bay Packers know they're headed to the playoffs, but who will they face when they get there? Here are the likeliest possibilities.

The Seattle Seahawks barely beat the Chicago Bears 6-3 in Week 17 of Thursday Night Football. Here are winners and losers ...

SportsLine's advanced model has locked in its Week 17 NFL betting picks and Week 17 NFL football predictions from 10,000 ...

Set your Championship Week lineups with start/sit advice from every game on the Saturday and Sunday slate in Week 17.

Coach Nick Sirianni's team has a chance to clinch an NFC East title Sunday at Lincoln Financial Field and his best move might ...