A new study from researchers at Max Planck Florida Institute for Neuroscience (MPFI) has shed light on the unexpected mechanism that allows calcium/calmodulin-dependent protein kinase, or CaMKII ...

Kinetics of endogenous CaMKII required for synaptic plasticity revealed by optogenetic kinase inhibitor. Neuron , 2017 DOI: 10.1016/j.neuron.2017.02.036 Cite This Page : ...

An improved reporter identifies ruxolitinib as a potent and cardioprotective CaMKII inhibitor. Science Translational Medicine , 2023; 15 (701) DOI: 10.1126/scitranslmed.abq7839 Cite This Page : ...

Forty years since its discovery, much remains to be discovered about an enzyme called CaMKII that plays a key role in shaping learning and memory in the brain. Now Roger Colbran, Ph.D., graduate ...

Researchers say a new study shows that activating the CaMKII pathway helps protect retinal ganglion cells from injuries, and in multiple glaucoma models. genprowebdirectory ...

CRD-2015 and CRD-2959 both inhibit CaMKII-mediated phosphorylation of phospholamban and the ryanodine receptor, two wellknown myocardial CaMKII targets, in cells and in rats in vivo.

Researchers at Vanderbilt University Medical Center and Erasmus Medical Center show that preventing the inhibition of CaMKII reverses the neurological deficits in a mouse model of Angelman ...

While CaMKII, an enzyme, has some functions in the heart, experiments in animals have shown that it isn’t essential, Reyes Gaido and his team noted in their paper. On top of that, there’s ...

Next Generation Cardiovascular Biotech to Present non-clinical Data on Two of its Novel, Potent, and Highly Selective CaMKII InhibitorsFirst Company to Study a CaMKII Inhibitor in a Clinical ...