Retinal diseases: RNA therapeutics show promise but is India ready?
Discover the importance of vision, genetic eye disorders, and RNA-based therapies for precision treatment in India and ...
ophthalmologytimes2d
Viralgen and Axovia Therapeutics partner to manufacture gene therapy for Bardet-Biedl Syndrome
The companies will work together by using the codon-optimized BBS1 AAV9 vector to minimize the vision loss caused by the ...
eLife11d
Wnt specifically induces FZD5/8 endocytosis and degradation and the involvement of RSPO-ZNRF3/RNF43 and DVL
Frizzled (FZD) proteins are the principal receptors of the Wnt signaling pathway. However, whether Wnt ligands induce FZD endocytosis and degradation remains elusive. The transmembrane E3 ubiquitin ...
Le Lézard8d
Viralgen and Axovia partner to manufacture an investigational gene therapy for retinal dystrophy in Bardet-Biedl Syndrome (BBS) patients
Viralgen and Axovia Therapeutics are joining forces to advance the development and manufacture of an AAV9-based investigational gene therapy aimed at treating retinal dystrophy in patients with Bardet ...
Nature6d
Codon Usage Bias and Gene Expression
Codon: A sequence of three nucleotides in DNA or RNA that corresponds to a specific amino acid or stop signal during protein synthesis. Synonymous mutation: A change in the DNA sequence that does ...
C&EN13d
DNA repeat expansion drives Huntington’s development
Studies of living participants and postmortem brains confirm that gene expansion is a promising target for HD prevention ...
Firstpost25d
Covid originated in China’s Wuhan lab? There’s now ‘smoking gun’ evidence, says Rutgers scientist Richard Ebright
The furin cleavage site of SARS-CoV-2 has codon usage —the pattern of preferences among synonymous three nucleotide sequences encoding amino acids in the genetic code— that is highly unusual for a ...