Combined treatment with IGF-1R/PI3K and MEK inhibitors induced death of BRAF ... This may indicate that changes of Src involvement in the control of Akt/PKB activity and its downstream signaling were ...

Extracellular ligand binding induces receptor dimerization, which activates several intracellular cascades including MAPK, PLC/PKC, SRC, JAK/STAT, and PI3K/AKT. These signaling pathways induce ...

According to the PPI diagram, the potential targets of Sufentanil for pulmonary sepsis included JAK2, SRC, FYN, KDR, GSK3B ... EGFR tyrosine kinase inhibitor resistance, PI3K-Akt signaling pathway, ...

The p160 SRC family contains three homologous members, SRC1, SRC2 and SRC3, that interact with nuclear receptors and specific transcription factors. They recruit chromatin remodelling and other ...

SRC president Nombulelo Chiya says the initiative plans to raise R15 million which the university will match making R30 million available for the cause. Wits University's great hall. Picture ...

Roche’s freshly approved PI3K inhibitor Itovebi can help extend the lives of certain patients with breast cancer when used in ...

In amongst a clutch of discontinued phase 3 programmes in Roche's fourth-quarter results update was the news that it has stopped a study of AKT inhibitor ipatasertib as a treatment for first-line ...

The DF-O and MPs samples suppressed autophagy by decreasing expression levels of microtubule-associated protein light chain 3 (LC3B), p-phosphatidylinositol 3-kinase (p-PI3K), phosphorylated AKT ...

Najib, 71, had testified in his earlier trial over SRC International Sdn Bhd’s RM42 million, which resulted in the former prime minister serving his six-year jail term now. In his 15th day of ...

Faculty of Pharmacy and Research and Innovation Hub, Alamein International University, Alamein, Matrouh 51718, Egypt Department of Pharmacology and Toxicology, Faculty of Pharmacy, Alexandria ...

PHP is a popular general-purpose scripting language that is especially suited to web development. Fast, flexible and pragmatic, PHP powers everything from your blog to the most popular websites in the ...