In this issue, Jiang et al. introduce a proteomic method called LoopID and show that JMJD2 demethylases have a non-catalytic role in promoting enhancer–promoter looping in mouse embryonic stem cells.

A broken chromosome must find an identical DNA sequence among billions of bases packed into the nucleus. Although homologous recombination solves this problem with remarkable accuracy, how the repair ...

The far-right proposal to cap Switzerland’s population at 10 mln, scheduled for a referendum in June, would damage the economy and likely struggle ⁠to translate into coherent measures. It still ...