Conversely, mTORC1 can suppress autophagy by inhibiting both ULK1 and beclin-1 complexes ... mTORC, mTOR complex; PGC-1α, peroxisome proliferator-activated receptor γ coactivator-1α; PI3K/AKT, ...

The term "God complex" is used to describe a person who believes they have exceptional power or authority and are superior to others. It is not considered a mental illness on its own, per the ...

Complex post-traumatic stress disorder (C-PTSD) is a mental disorder that develops in response to complex trauma during childhood. Complex trauma is defined as prolonged exposure to traumatic events ...

Once the autophagic induction has been triggered, the class III PI3K complex allows the formation of the phagophore. The Beclin-1 complex is constituted by Beclin-1, ATG14, vacuolar protein sorting 34 ...

Fully connected neural networks in the infinite-width limit often outperform finite-width models, while convolutional networks excel at finite widths. Here, the authors uncover how convolutional ...

Based on the PDZ domains, postsynaptic density-95 (PSD-95) assembles GluN2B and nNOS into a macromolecular complex. After being overactivated ... The PKD–JNK pathway as well as autophagy induced by ...