The biogenesis of EVs is a complex process that involves multiple cellular pathways ... of protective networks within the cardiovascular system, including the AMPK/PI3K/AKT pathway, transforming ...

Western blot analysis was performed to examine the components of the PI3K/AKT signaling pathway. Results: Among the sixty-four shared targets identified, JUN and CCND1 were the most frequently ...

RAF, PI3K and the RAL guanine exchange factor (RAL ... and NF-κB activation are required for KRAS-induced tumorigenesis. Autophagy counterbalances cellular stress associated with oncogenic ...