Alpha-fetoprotein (AFP ... CD133/CD44 and EPCAM by activating the PI3K/AKT signaling pathway, thereby promoting the expansion of LCSCs. In addition, AFP can directly upregulate the expression of LCSCs ...

In living organisms, protein molecules with different chemical structures called proteoforms, are produced from a single gene to perform a variety of physiological protein functions. It has been ...

A prominent research group from Ehime University and its close partner at Kiel University have published their third ...

Scroll through TikTok or Instagram and you’ll be inundated with protein-centric recipes. Maximizing protein is a huge trend right now on social media—and not just in the usual suspects ...

She has spent most of her career counseling patients with diabetes, across all ages. Creatine and protein both play essential roles in the body. Creatine is necessary for energy production and ...

Don’t overlook fruit when trying to add more protein to your diet. Fruit may not make the list of high-protein foods, but some options can provide the essential macronutrient, with the added ...

This review highlights recent progress regarding the critical components of the JAK2-STAT5 pathway and its crosstalk with G-protein coupled receptor (GPCR) signaling, PI3K-Akt signaling, growth ...

They found no evidence of hyperactive PI3K signalling monitored by pAKT in a APDS2 patient-derived dermal fibroblast cells. In these cells p110 alpha protein levels were comparable to levels in ...

The pharma group did not break down the details of the license to get control of STX-478, described as a next-generation PI3K alpha inhibitor for breast cancer and other advanced solid tumours ...

The recent acquisition of Scorpion Therapeutics for approximately $2.5 billion is set to bolster Eli Lilly's oncology portfolio, particularly in advancing PI3K-alpha mutant selective therapies for ...