A therapeutic Porphyromonas gingivalis gingipain vaccine induces neutralising IgG1 antibodies that protect against experimental periodontitis. NPJ Vaccines , December 2016 DOI: 10.1038/npjvaccines ...

P. gingivalis also produces proteases, and these are divided into two distinct families - cysteine proteases and serine proteases. These enzymes are also known as “gingipains” and are secreted by P.

The phase I clinical trial, which was conducted in Australia, assessed the tolerability, safety and immunogenicity of the Avacc 10 ® vaccine. In a randomized, double-blinded, placebo and OMV ...

P. gingivalis induces a local inflammatory response that results in oral bone destruction, which is manifested as periodontal disease, an inflammatory disease that affects approximately 100 ...

Porphyromonas gingivalis-derived OMV vaccine Periodontitis is the most prevalent infectious disease related to oral and systemic health, and a novel prophylaxis to prevent the disease is therefore ...

Keystone Bio announces Porphyromonas Gingivalis Toxic Virulence Factors as a Major Driver of Sporadic Alzheimer’s and Chronic Inflammation.

Novartis’s rMenB-OMV Meningococcal Vaccine and Merck’s V-503 HPV Vaccine Are Expected to Each Garner Blockbuster Sales in Excess of $2 Billion in 2020 . Human ...

Subgingival P. gingivalis was cultured before treatment from 2,193 adults with severe periodontitis in the USA during three time periods: 1999-2000 (936 patients); 2009-2010 (685 patients), and ...