Parsons said the study results "pretty much close the chapter of tenecteplase versus alteplase in the early treatment window for thrombolysis in ischemic stroke (within 4.5 h of symptom onset).

Intravenous thrombolysis with alteplase is used in eligible patients with acute ischemic stroke before endovascular thrombectomy. 1,2 Alteplase is given as an infusion over a period of ...

Seeking to determine the safety and efficacy of IV tenecteplase compared with alteplase for patients with acute ischemic stroke not eligible for endovascular thrombectomy, researchers conducted a ...

Eligible patients had onset of stroke 4.5 to 24 hours before randomization, a posterior circulation Acute Stroke Prognosis Early CT Score (PC-ASPECTS; scores range from 0 to 10, with lower scores ...

The older the patient, the worse the functional outcome tended to be after endovascular thrombectomy (EVT) for an acute ischemic stroke with a large infarct, observational data suggested. Based on ...

“The best outcomes, explains Dr. Modak, “occur when the medication is administered within 3 to 4.5 hours of the onset of ...

PHOENIX -- Endovascular thrombectomy for large-core acute ischemic stroke improved long-term outcomes, the SELECT2 trial affirmed. The intervention shifted the 1-year modified Rankin Scale (mRS ...

The Food and Drug Administration (FDA) has approved TNKase ® (tenecteplase) for the treatment of acute ischemic stroke (AIS) in adults.. The approval was supported by data from the registry ...

Similarly, the risk of 90-day mortality (mRS score of 6) was increasingly unfavorable with older age (P<0.001):15.4% at age 60 and below; 31.8% in those 61-70 ...