Figure 1: The signalling pathway by which insulin inhibits GSK3 and contributes ... 3-phosphoinositide-dependent protein kinase 1; PKB/AKT, protein kinase B; S6K, ribosomal protein S6 kinase.) ...
Tyrosine-protein phosphatase non-receptor type 1 (PTP1B) acts as a negative regulator of the insulin signaling pathway by dephosphorylating both the insulin receptor (IR) and the insulin receptor ...