Heart failure (HF) is a growing global health concern, affecting more than 64 million people worldwide. It develops when the heart can no longer pump enough blood to meet the body's demands, often due ...

ABSTRACT To identify what makes insulin have an activating or inhibiting role in gluconeogenesis in goose hepatocytes and whether insulin regulates PEPCK and G6Pase through the PI3k/Akt/mTOR pathway ...

Likewise, such effects of DCI were confirmed in HepG2 cells with palmitate-induced insulin resistance. These findings indicate a novel pathway by which DCI prevents hepatic gluconeogenesis, reduces ...

Researchers from Osaka Metropolitan University have identified a gene that, when activated by metabolic stress, damages ...

News Release 17-Jun-2025 New hormonal pathway links oxytocin to insulin secretion in the pancreas Peer-Reviewed Publication Impact Journals LLC image: Figure 2. Relation of Oxt and glucagon.

Researchers from Osaka Metropolitan University have identified a gene that, when activated by metabolic stress, damages ...

This is a useful study in the role of CHI3L1 in Kupffer cells, the macrophages of the liver, showing that CHI3L1 alters glucose regulation in obesity. Specifically, Chi3l1 protects glucose-dependent ...

A massive U.S. study found diabetics on semaglutide (Ozempic’s active ingredient) had up to 70% lower risk of ...

Experts warn the real AI threat is not destruction, but subtle manipulation that makes us surrender willingly.

The failure to develop diabetes in mice with a selective impairment of insulin signaling in muscle can be explained by two compensatory pathways: the IGF1 receptor (Igf1r) pathway and the ...

The Insulo-Acinar Axis and Metabolic Compensation to Insulin Resistance Although it is clear that β-cells can proliferate in response to a host of growth factors, the most parsimonious ...