Cryo-EM structure of Sudan ebolavirus glycoprotein complexed with its human endosomal receptor NPC1 - (https://www.nature.com ...

The Sudan virus, a close relative of Ebola, has a fatality rate of 50% but remains poorly understood in terms of how it infects cells. Currently, no approved treatments exist. To address this critical ...

Feb. 4, 2025 — The Sudan virus, a close relative of Ebola, has a fatality rate of 50% but remains poorly understood in terms of how it infects cells. Currently, no approved treatments exist. To ...

Structure-based drug design is the design and optimization of a chemical structure with the goal of identifying a compound suitable for clinical testing — a drug candidate. It is based on ...

One example is a family of potentially deadly viruses known as filoviruses, which includes Ebola. The largest outbreak of Ebola happened between 2014 and 2016, with more than 11,000 people killed.