Research indicates that RanBPM stabilizes the cell cycle regulator p21 by preventing its degradation through a process called deubiquitination. This stabilization is crucial for maintaining proper ...

We previously demonstrated the involvement of YAP (Yes-associated protein) in high-fat/high-sucrose diet (HFHSD)–induced arterial stiffness via modulation of PPM1B (protein phosphatase Mg 2+ /Mn 2+ ...

Ubiquitination label-free quantitative proteomic analysis was performed to identify protein peptides that may potentially undergo deubiquitination by USP9X. It was also validated in vivo and in vitro ...

Future Virology. 2010;5(4):469-479. Other viral proteases that permit the virus to escape the host immune response have been described. Severe acute respiratory syndrome-associated coronavirus ...

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Target Discovery Institute, Centre for Medicines Discovery, Nuffield Department of Medicine, University of Oxford, Oxford, OX3 7FZ, U.K. ARUK-Oxford Drug Discovery Institute, Centre for Medicines ...

Bronchopulmonary dysplasia is a prevalent respiratory disorder posing a significant threat to the quality of life in premature infants. Its pathogenesis is intricate, and therapeutic options are ...

1 Graduate School, Heilongjiang University of Chinese Medicine, Harbin, China 2 Department of Critical Care Medicine, First Affiliated Hospital of Heilongjiang University of Chinese Medicine, Harbin, ...

Clinical Physiology provides diagnostic methods to detect and evaluate dysfunction of various organs and systems in the body such as the heart, peripheral vessels, lungs, kidneys, gastrointestinal ...