In the early days of President Donald Trump’s second term, Alaska Sen. Lisa Murkowski had openly challenged or rebuked him at least three times.

Sen. Lisa Murkowski is opposing the nomination of Pete Hegseth to be President Donald Trump's Defense secretary.

Lisa Murkowski, the senior United States senator from Alaska, has held the seat since 2002. When will she be up for re-election? Here's what we know.

Senators Lisa Murkowski, Susan Collins and Mitch McConnell voted against confirming Donald Trump’s pick for defense secretary. To Capitol insiders, their decisions weren’t surprising.

U.S. Sen Lisa Murkowski was alone in stridently opposing Trump’s blanket pardon for Jan. 6 defendants, and his order to rename Denali as Mount McKinley.

Alaska U.S. Sen. Lisa Murkowski on Thursday announced on social media that she would vote against confirming Pete Hegseth to lead the U.S. Department of Defense. Republicans have a 53-seat majority in the U.

President Donald Trump said Friday that he wasn't expecting Republican Sens. Lisa Murkowski (Alaska) and Susan Collins (Maine) to vote against his controversial nominee for secretary of Defense, Army veteran and former Fox News host Pete Hegseth.

WASHINGTON (AP) — The Senate is muscling Pete Hegseth’s nomination as defense secretary toward confirmation Friday, prioritizing his vow to create a “warrior culture” at the Pentagon over allegations of heavy drinking and aggressive behavior toward women.

President Donald Trump said he was “surprised” that Republican Sens. Susan Collins (Maine) and Lisa Murkowski (Alaska) voted to oppose Pete Hegseth’s defense secretary nomination.

Moderate GOP Sen. Lisa Murkowski of Alaska has broken her silence, saying she won't be voting to confirm Pete Hegseth as secretary of defense.

Murkowski is a moderate with a history of bucking her party and Trump when she has felt it was the right thing to do.

Sen. Lisa Murkowski announced Thursday that she will vote against confirming Pete Hegseth to lead Pentagon, becoming the first Republican to oppose one of President Donald Trump’s Cabinet picks.