Journal of Neurology, Neurosurgery and Psychiatry (JNNP)

Current Issue

Short report: Cluster analysis showed long-term cognition can be predicted by looking at regional grey matter atrophy in the ...
BMJ

Comparison between plasma and cerebrospinal fluid biomarkers for the early diagnosis and association with survival in prion disease

Correspondence to Professor Piero Parchi, Dipartimento di Medicina Specialistica Diagnostica e Sperimentale, Università di Bologna, Bologna 40138, Italy; piero.parchi{at}unibo.it Objective To compare ...
BMJ

Anti-CASPR2 clinical phenotypes correlate with HLA and immunological features

Objective Antibodies against contactin-associated protein-like 2 (CASPR2-Abs) have been described in acquired neuromyotonia, limbic encephalitis (LE) and Morvan syndrome (MoS). However, it is unknown ...
BMJ

The future of neuroprotection in stroke

Investigators acknowledge the limitations of rodent or non-human primate stroke models, hundreds of putative neuroprotectants have been evaluated in preclinical models, but not one has entered the ...
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Cognitive impairment in Parkinson’s disease

Department of Neuropsychology, Leiden University Medical Centre, Leiden, the Netherlands D Verbaan, Department of Neurology, K5Q-92, Leiden University Medical Centre, PO Box 9600, NL- 2300 RC Leiden, ...
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The deep tendon and the abdominal reflexes

The deep tendon reflexes (and the abdominal reflexes) are important physical signs which have a special place in neurological diagnosis, particularly in early disease when they alone may be abnormal.
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EEG in the diagnosis, classification, and management of patients with epilepsy

The human electroencephalogram (EEG) was discovered by the German psychiatrist, Hans Berger, in 1929. Its potential applications in epilepsy rapidly became clear, when Gibbs and colleagues in Boston ...
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Progressive biparietal atrophy: an atypical presentation of Alzheimer's disease.

OBJECTIVES: To define the clinical, neuropsychological, and radiological features of bilateral parietal lobe atrophy. METHODS: Four patients underwent a comprehensive longitudinal neuropsychological ...
BMJ

The EQ-5D—a generic quality of life measure—is a useful instrument to measure quality of life in patients with Parkinson's disease

OBJECTIVE To test the feasibility and validity of the EQ-5D (a widely used generic (disease non-specific) quality of life (QoL) instrument which allows comparisons between different patient groups and ...
BMJ

Arnold-Chiari-II malformation and cognitive functioning in spina bifida

1 Department of Medical Psychology, Radboud University Medical Centre, Nijmegen, The Netherlands 2 Department of Pediatric Neurology, Radboud University Nijmegen Medical Centre Correspondence to: A ...
BMJ

Sodium valproate for tinnitus

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