Hyperrelexic, overactive or spastic bladder or bowels occur with spinal cord injury at or above T12. The primary characteristic of this type of injury is increased organ spasms. The UMN bladder may ...
Meeting the challenges of Huntington’s disease and upper motor neuron diseases like ALS These are exciting times for neurological disease research and the discovery of new therapeutic strategies for ...
Primary lateral sclerosis (PLS) is a rare neurological disorder that affects the motor neurons in the brain and spinal cord, which control movement. It is a form of motor neuron disease (MND). PLS ...
Motor neurons are some of the largest cells in the human body. In particular, upper neurons—extending from the cerebral cortex to the brain stem or spinal cord—average 60μm in diameter. 3,4 These ...
Progressive muscular atrophy (PMA) is a rare adult-onset motor neuron disease. Although there’s no cure, treatments may slow down nerve damage and reduce symptoms. Progressive muscular atrophy (PMA) ...
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Living well with primary lateral sclerosis
Primary lateral sclerosis (PLS) is a rare, progressive condition that affects upper motor neurons, leading to stiffness, spasticity, and mobility challenges. While there’s no cure, symptom-focused ...
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