The immune system’s capacity to distinguish self from non-self is in large part mediated by immunoglobulins, with IgG playing a pivotal role in both protective and pathological responses.
Immunoglobulins are central to shaping immune responses and are critical tools for probing biological mechanisms in biomedical research. However, selecting an inappropriate antibody isotype can lead ...
In a recent study published in Immunity, researchers isolated SARS-CoV-2 spike (S) protein-targeted mAbs (monoclonal antibodies) from convalescent healthcare workers (HCWs), emphasizing the IGHV1-69 ...
In a recent study published in Science Translational Medicine, researchers evaluated the differential humoral immune response to two coronavirus disease 2019 (COVID-19) vaccines - messenger ...
A new study shows how the single-molecule organization of receptors in a cellular context determines the function of antibodies, opening up new pathways for the development of cancer immunotherapies.
Antibodies—proteins that are produced by our immune system to protect us—are crucial for recognizing and getting rid of unwanted substances, or antigens, in our body. Although their role is universal, ...
Pontus Nordenfelt (left, photo by Tove Smeds) is an Associate Professor and Senior Lecturer at Lund University (Sweden) who uses a range of techniques to study initial host–pathogen interactions. In ...
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Super-resolution microscopy reveals nanoscale architecture of antibody-receptor interactions
A new study shows how the single-molecule organization of receptors in a cellular context determines the function of antibodies, opening up new pathways for the development of cancer immunotherapies.
CD BioGlyco leverages its state-of-the-art platform and years of experience to deliver precise and consistent modifications to your antibody glycans. Researchers can now access homogeneous glycoforms ...
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