Epithelial cells are joined by adherens junctions, which consist of homotypic interactions between extracellular domains of E-cadherins. Inside the cell, the tails of E-cadherins bind actin cables ...

The linkage of adherens junctions to the actin cytoskeleton is essential for cell adhesion. The contribution of the cadherin–catenin complex to the interaction between actin and the adherens junction ...

The homeostasis of adherens junctions was studied using E-cadherin and its two mutants tagged by the photoconvertible protein Dendra2 in epithelial A-431 cells and in CHO cells lacking endogenous ...

Epithelial cells are held together and connected by several different types of structures that form cell-cell contacts. One of these structures, found near the top surface of the cell, is the adherens ...

The molecular mechanisms responsible for the formation of the adherens junction at the nanoscale level have been revealed by researchers in a new article. Although the cells that make up our body are ...

Researchers report the first evidence in living organisms that adherens junctions, the 'glue' between cells, actively respond to mechanical cues by remodeling their position and intensity, which in ...

Embryonic development, wound healing or cancer metastases: cell-to- cell adhesion plays an important role in these and many other patho-physiological processes. The cellular mechanisms behind this ...

Cell-to-cell junctions were visualized by ZO1-GFP, and the dynamics of cell junctions were captured by movies. When the cells indicated by * were spontaneously stretched, a continuous belt of cell ...