Inosine is a nucleoside that occurs naturally in transfer RNAs (tRNAs) and is essential for proper RNA translation. It is commonly found at the wobble position of anticodons, allowing for greater ...
Figure 1: Proposed chemical mechanism for the biosynthesis of cmo5U. Figure 2: Structure of the CmoA–Cx-SAM complex. The fortuitous identification of a bound ligand in a crystal structure (such as ...
tRNAs have a distinct cloverleaf secondary structure and an L-shaped tertiary structure. The cloverleaf structure is formed by the folding of the single-stranded tRNA molecule, which is typically ...
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