Researchers have uncovered a surprising molecular chain reaction in the brain that may play a role in some forms of autism.

The human brain develops through an intricate balance of cellular growth, connectivity, and metabolism. A new study reveals ...

Chief Executive Officer Brian Sullivan outlined the company’s clinical and commercial priorities for its lead asset, ...

Individuals with certain comorbidities, such as obesity and diabetes, are at a higher risk of being severely infected with severe acute respiratory syndrome coronavirus-2 (SARS-CoV-2), the causal ...

An interview with David M. Sabatini, M.D., Ph.D., conducted by April Cashin-Garbutt, MA (Cantab). Can you please give a brief introduction to the mechanistic target of rapamycin (mTOR) cellular ...

Learning more about the mTOR complex and how it works is a stepping stone for others who might look for cancer therapies or ways to help treat diabetes and other diseases. In the world of biology, ...

Network map of 29 authors with frequency greater than five. Nodes represent authors, and the larger the node, the higher the number of papers. The lines represent collaborations with other authors, ...

Prognostic value of hedgehog signaling in cervical carcinoma. Background: Although improvements in the treatment of ovarian cancer have increased the global prognosis, the metastatic disease is still ...

Fig 1. PI3K/AKT/mTOR signaling pathway showing interacting activation and regulatory feedback loops. Adapted from Hoeffer and Klann. 35 Mammalian target of rapamycin (mTOR) is a serine-threonine ...