A new study in iScience shows that blocking the cannabinoid CB1 receptor with low-dose rimonabant reverses disease-associated ...

Preeclampsia is a pregnancy complication with serious risks for mother and child. The only real cure for preeclampsia is delivery. Now, a new mouse study reports that high levels of an mRNA splicing ...

New data suggest that cellular stress and immune activation via the type 1 interferon (IFN1) pathway may be therapeutic ...

RNA is the means of translating the genetic code embedded in DNA into proteins, which serve as enzymes, transporters, signaling molecules, receptors, structural components, regulators, and ...

Illustration of the three-dimensional structure of the trans-spliceosome, the molecular machine responsible for a key stage ...

Background Next-generation sequencing of cancer predisposition genes is routinely used in hereditary cancer diagnostics.

A study finds that mammalian cells can join RNA from separate genes into functional hybrid proteins, revealing a hidden layer ...

A conserved Lsm8-exosome module that safeguards RNA splicing fidelity has been revealed as a master switch controlling growth ...

Immunotherapy has been a revolutionary breakthrough for cancer therapeutics, but it is still hampered in that it only benefits certain patients. Moreover, the molecular determinants of immunotherapy ...

In an important new study, Chinese researchers have discovered the previously unrecognized role of alternative splicing of the DOC2A gene in schizophrenia. The research was conducted by scientists led ...