The EGFR pathway has an important role in modulating angiogenesis, metastasis, cell survival and proliferation (Figure 1); therefore, inhibition of this pathway is being explored for therapeutic ...

Researchers from SRM Institute of Science and Technology, led by Dr. KN Aruljothi, have published a study in ExRNA ...

Assessment of transfer entropy is useful for network analysis of cell signaling network providing information on the network topology and action points of genetic mutations and drug effect, thus will ...

Significant progress was made in 2024, including refining the Phase 3 program to accelerate rilparencel’s path to market in the U.S., the release ...

Rapid eGFR decline occurred in 23% of patients on ... “Physical exercise is known to mitigate several of these pathways, preventing vascular diseases in the heart, brain and musculoskeletal ...

How can we tell whether EGFR inhibitors effectively inhibit the key pathways driving EGFR-mediated radioresistance? Considering tumor instability and heterogeneity, how can we optimize the ...

Despite advancements in EGFR-targeted therapies ... downstream molecules within the RAS-RAF-MEK-ERK and PI3K-AKT-mTOR pathways. Furthermore, the study explores the intricate relationship between ...

NT219 in combination with EGFR antibody cetuximab (Erbitux) is currently entering a Phase 2 study for head and neck cancer REHOVOT, Israel, March ...