Nebulin is a giant modular sarcomeric protein that has been proposed to play critical roles in myofibrillogenesis, thin filament length regulation, and muscle contraction. To investigate the ...

The human heart, often described as the body's engine, is a remarkable organ that tirelessly beats to keep us alive. At the core of this vital organ, intricate processes occur when it contracts, where ...

Osaka, Japan - Researchers at Osaka University used electron cryomicroscopy (CryoEM) to image essential cardiac muscle components, known as thin filaments, with unprecedented resolution. They also ...

An international team of scientists from the University of Florence, Italy and the Randall Division in collaboration with the ESRF, the European Synchrotron, Grenoble, France, demonstrated a new ...

Join the UMove Journal Club Friday, Dec 2 at 9:30 a.m. in Olsen 235 for free donuts and a discussion on how "Titin force in muscle cells alters lattice order, thick and thin filament protein formation ...

Atrial fibrillation, heart failure and stroke – hypertrophic cardiomyopathy can lead to many serious health conditions and is a major cause of sudden cardiac death in people younger than 35. „The ...