Study shows that activity in the subthalamic nucleus reflects action outcomes and consequent adaptation in humans; this can be modified through bursts of electrical stimulation, with potential to ...

A French study has shown that deep brain stimulation can improve symptoms of obsessive–compulsive disorder (OCD). Serotonin reuptake inhibitors and behavioral therapy constitute the standard treatment ...

(A) Experimental design. (B) Behavior assessments using open field tests. Heatmaps illustrate time spent (red) and movement trajectories (green). The PD group exhibited decreased movement speed ...

Researchers have applied a chemogenetic tool in macaque monkeys and suppressed the subthalamic nucleus, a part of the basal ganglia circuitry. The chemogenetic suppression induced unstable movements.

Deep brain stimulation is a key procedure in the treatment of Parkinson's disease. Researchers have now identified the ...