Antidepressants treat symptoms of depression by increasing levels of brain signaling molecules (neurotransmitters) such as serotonin, as with the most widely used type of antidepressant, selective ...

Researchers identified a protein production switch in hippocampal mossy cells that explains delayed antidepressant effects. Chronic SSRI use increases PACAP neuropeptide signaling, gradually reshaping ...

Recent research has opened the debate on whether chemical imbalances cause depression, anxiety, and other conditions ...

A research team led by Professor Oh Yong-Seok of the Department of Brain Sciences at the Daegu Gyeongbuk Institute of Science ...

Mechanism of brain neuropeptide circuit reconstruction uncovered, paving the way for next-generation rapid-acting therapies beyond serotonin - Findings published in Molecular Psychiatry, a leading jou ...

A new brain-imaging study has revealed how ketamine produces its fast antidepressant effects in people with treatment-resistant depression. Researchers tracked changes in a critical brain receptor ...

A web-based tool that incorporates patient preference in antidepressant selection was associated with a significant decrease ...

Major depressive disorder (MDD) is one of the leading causes of disability worldwide, and approximately 30% of patients develop treatment-resistant depression (TRD), a condition that does not respond ...