Female fertility and reproductive health depend on a series of developmental steps from embryogenesis through puberty, in addition to the proper functioning of the reproductive system in adulthood.

Mammalian sexual differentiation unfolds as a tiered process, starting with chromosomal sex pairing during fertilization, proceeding with gonadal sex determination, and terminating with sex hormone ...

Early in human development, during the first trimester of gestation, a fetus may have XX or XY chromosomes that indicate its sex. Yet at this stage a mass of cells known as the bipotential gonad that ...

From invisible wafts of diesel exhaust to sun-choking plumes of orange smoke, air pollution is known to damage respiratory well-being. Now, research suggests another reason to hold our breath: ...

Two hormone-like compounds linked to the consumption of soy-based foods can cause irreversible changes in the structure of the brain, resulting in early-onset puberty and symptoms of advanced ...

Genetic conditions often result from inherited mutations passed down from one or both parents. In an inherited genetic disorder, a mutated gene is transmitted from a parent. 3 Recent developments have ...

New research has mapped the cell types that specialise to form reproductive organs in both sexes, identifying key genes and signals that drive this process. The findings offer important insights into ...

An endocrinologist is a doctor who specializes in the endocrine system. This network of glands inside your body creates hormones that help cells talk to each other. The endocrine system is varied and ...

In the introduction to her latest book, “GUYnecology: The Missing Science of Men’s Reproductive Health,” Yale sociologist Rene Almeling describes a day in the life of “John,” a regular guy who is ...