Pharmacology: The use of opioid analgesics can lead to constipation due to their effect on intestinal smooth muscle and their interference with the bowel’s normal elimination function.
Methylnaltrexone bromide (Relistor) is FDA-approved to help restore bowel function in patients with opioid-induced constipation in late-stage, advanced illness (FDA Press Release. April 24, 2008). A ...
About 9-12 million Americans suffer from chronic pain annually, and most are prescribed opioid medications to treat and control their symptoms 1. While opioids can help relieve and manage chronic pain ...
WASHINGTON (Reuters) - Wyeth and Progenics Pharmaceuticals Inc won U.S. approval to sell a new drug to relieve the constipation that often occurs with use of morphine or other opioid painkillers, ...
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