Place a 2,000 ml three-necked round-bottomed flask in a heating mantle. Equip the reaction flask with a 250 ml addition funnel and a mechanical stirrer. Flush the flask with argon for 30 min. Add 104 ...
Even though amide bonds are everywhere—they hold proteins together and are essential components in many drugs—forging this molecular motif in a reaction flask can be challenging. For example, making ...
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