In this review of RNA therapies, we paint an overview of what’s going on in a field that is addressing a number of diseases.

RNA (ribonucleic acid) plays a crucial role in various biological processes, including gene expression and regulation. Understanding the structure of RNA is essential because its function is ...

Researchers have now uncovered the 3D structure of the RNA enzyme SAMURI. Their study provides insights into the development of ribozymes and the evolution of catalytically active RNA. Researchers ...

Researchers mapped HIV-1’s translation strategy, revealing RNA elements like uORFs, iORFs and an intricate frameshift site ...

Researchers led by chemist Claudia Höbartner have now uncovered the 3D structure of the RNA enzyme SAMURI. Their study provides insights into the development of ribozymes and the evolution of ...

A team of scientists at the Helmholtz Institute for RNA-based Infection Research (HIRI) in Würzburg and the University of Regensburg has unveiled insights into how HIV-1, the virus responsible for ...

No large RNA structure database exists that correlates sequence with 3D topology. Successful protein-centric methods like AlphaFold remain unavailable for RNA, creating a critical gap in ...

Simulations were supported by wet lab experiments using nuclear magnetic resonance (NMR), which confirmed that CG-MD can reveal detailed insights into the structure and behavior of RNA nanoparticles.