In the present work, we determine a crystal structure of FPPS in complex with FPP. Intriguingly, the product is bound not to the active site, but to the speculated allosteric pocket of the enzyme.
Rhomboid, birefringent calcium pyrophosphate (CPP) crystals are seen under polarizing light microscopy in this sample of synovial fluid that was obtained from a patient with acute CPP crystal ...
Researchers have discovered two genes, RNF144B and ENPP1, that cause calcium pyrophosphate deposition (CPPD) disease in Americans of European and African descent. This crystalline arthritis is caused ...
Many of us have had the experience of looking at a nutrition label and hardly even recognizing the ingredients. You might have seen one such ingredient popping up frequently — sodium acid ...
Fracture risk is nearly doubled in individuals with acute calcium pyrophosphate (CPP) crystal arthritis, according to a study recently published in Arthritis & Rheumatology. Sara K. Tedeschi, M.D., ...
In a first-of-its-kind genome-wide association study (GWAS) researchers have discovered two genes, RNF144B and ENPP1, that cause calcium pyrophosphate deposition (CPPD) disease in Americans of ...
Chondrocalcinosis is a finding from an imaging scan, describing when crystals made up of calcium pyrophosphate buildup in the joints. The condition that causes chondrocalcinosis is called calcium ...
Please provide your email address to receive an email when new articles are posted on . Utilization of pyrophosphate imaging to identify patients with cardiac amyloidosis has increased, although ...
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