Intracellular protein trafficking and secretion of proteins into the extracellular environment are sequential and tightly regulated processes in eukaryotic cells. Conventionally, proteins that are ...

A group of international researchers reports the availability of a new “map”’ of every gene, protein, and metabolic pathway required for a cell to efficiently secrete recombinant proteins. The team, ...

Gram-negative bacteria deploy a suite of dedicated secretion pathways to traverse their dual-membrane envelope and deliver proteins critical for nutrient acquisition, environmental adaptation and ...

Intracellular protein trafficking and secretion of proteins into the extracellular environment are sequential and tightly regulated processes in eukaryotic cells. Conventionally, proteins that are ...

When cells utilize glucose as a carbon source, the HBP functions normally, maintaining intracellular O-GlcNAcylation at a high level. In this state, O-GlcNAc-modified SNAP25 stabilizes its interaction ...

Deep in our cells, a wide range of processes are occurring constantly. These cellular processes rely on enzymes to act as catalysts and set off a series of molecular interactions. There are still many ...

Oxidative stress induced by 6-OHDA stimulates autophagy flux, which enhances STX17-mediated autolysosome formation, leading to the degradation of autophagosomal contents. However, in response to ...