Protein AMPylation represents a specialised post‐translational modification (PTM) in which an adenosine monophosphate (AMP) moiety is covalently attached to specific amino acid residues on target ...
Lactylation, a recently identified post-translational modification, has emerged as important for immune regulation, tissue repair, cancer cell metabolism, and now, potentially, Alzheimer’s disease. In ...
Whole blood derived from six adult donors who were inoculated with BCG in their childhood was cultured with MDP1 alone, MDP1 in combination with G9.1, or in combination with the negative form of ...
Exploring the post-translational modifications of a key protein in Parkinson's disease, researchers uncover potential pathways for future therapies in neurodegenerative diseases in general.
Citrullination, a transformative protein post-translational modification, is gaining recognition for its wide-ranging impact on cellular function and human disease. This process, driven by the enzyme ...
Researchers at Baylor College of Medicine have developed an artificial intelligence (AI) model that reveals how protein modifications link genetic mutations to disease. The method, called DeepMVP and ...
The baculovirus-insect cell expression system is a potent and adaptable platform for protein production. The robust post-translational modification capabilities and relatively high cell culture ...
An Iowa State University research team has discovered a method for modifying the function of an enzyme crucial to fat production, which could lead to more effective treatments for childhood obesity ...
Researchers at Baylor College of Medicine have developed an artificial intelligence (AI) model that reveals how protein modifications link genetic mutations to disease. The method, called DeepMVP and ...
This overview explains how proteomics sample preparation underpins mass spectrometry performance. It details best practices ...
Enhancing protein identification accuracy is vital for proteomics; this article explores key technologies and statistical methods involved.