A structural protein best known for building the internal scaffolding of cells may double as a natural defense against the ...

Alcohol-associated liver disease (ALD) remains a leading cause of cirrhosis and liver-related mortality worldwide, with few effective therapies.

By watching Alzheimer’s-related protein clumping unfold second by second, researchers have uncovered new clues about the role of metal ions.

Researchers found that tubulin can guide Tau and alpha synuclein toward healthy roles in neurons instead of forming toxic aggregates. The findings suggest boosting tubulin levels may help protect ...

An Oregon State University scientist and a team of undergraduate students have uncovered real-time insights into a chemical process linked with Alzheimer's disease, paving the way toward better drug ...

Loss and dysfunction of synapses have been linked to age-related cognitive decline and observed in Alzheimer's and other ...

Protein-based therapeutics have transformed treatments for numerous diseases, yet their production remains highly complex and cost-intensive [1][2],[3][4]. Downstream processing (DSP), including ...

The formation of amyloid fibrils and the aggregation of misfolded proteins are central to the pathology of Alzheimer’s disease. At the molecular level, normal proteins adopt aberrant conformations ...

Protein aggregation is typical of various neurodegenerative diseases such as Alzheimer's, Parkinson's and prion diseases such as Creutzfeld-Jakob disease. A research team has now used new in vitro and ...

A protein best known for its role in Parkinson’s disease can accelerate Alzheimer’s-related brain changes by up to 20 times in patients who carry elevated levels of both pathologies, according to new ...

Tubulin acts as a master regulator, preventing Tau and alpha-synuclein from forming toxic clumps in Alzheimer's and Parkinson's.