We describe the clinical course of a patient with multiple sclerosis in whom progressive multifocal leukoencephalopathy (PML), an opportunistic viral infection of the central nervous system, developed ...

PML stands for progressive multifocal leukoencephalopathy. It’s an aggressive viral disease of the central nervous system. The virus attacks cells that make myelin. Myelin is a fatty substance that ...

Progressive multifocal leukoencephalopathy (PML) is a rare subacute demyelinating disorder of the central nervous system (CNS) caused by the DNA JC human polyomavirus. In immunocompromised hosts, PML ...

Over the next month, the weakness progressed to flaccid paralysis of the right arm and the patient had a seizure. Repeat MRIs showed progression of confluent hyperintense white-matter lesions ...

The following represents disclosure information provided by authors of this manuscript. All relationships are considered compensated. Relationships are self-held unless noted. I = Immediate Family ...

A 34 year-old HIV positive man had declined anti-viral treatment. Over the course of 3 weeks, he developed progressive ataxia affecting the left side. Progressive Multifocal Leukoencephalopathy (PML): ...

The Brief Reports on natalizumab were referred to Biogen Idec, the manufacturer, which offers the following response: After learning of one confirmed and one suspected case of progressive multifocal ...