The characteristics of an organism emerge through complex interactions of its genetic make-up and the effects of the environment. This article discusses this terminological distinction in genetics - ...

The gap between genotype and phenotype is filled by complex biochemical systems most of which are poorly understood. Because these systems are complex, it is widely appreciated that quantitative ...

Genotype–phenotype databases contain data on genetic variants and associated phenotypes. In medical contexts, such databases are focused on disease-causing mutations and resulting diseases or ...

Mating competition between Drosophila melanogaster males carrying different white eye color alleles on a uniform genetic background was studied. In an alternating light-dark environment, males ...

To determine the association between genotype and phenotype in patients with RB, the investigators conducted a single-center retrospective cohort study of 1404 consecutive unrelated individuals ...

New research shows that while a three-base pair, in-frame deletion called p.Met992del in the NF1 gene has a mild phenotype for people with the genetic disorder neurofibromatosis type 1, or NF1, the ...

Cancers are genetic diseases driven by recurrent sets of somatic mutations. Different mutations associate statistically with distinct disease risks and can therefore be useful prognostic markers. But, ...

National Institutes of Health researchers have published an assessment of 13 studies that took a genotype-first approach to patient care. This approach contrasts with the typical phenotype-first ...

Bacterial populations pose an intriguing puzzle: in so-called isogenic populations, all bacteria have the same genes, but they still behave differently, for example grow at different speeds.

Genotype to phenotype: interpretations of the human genome project / Sue Malcolm -- From protein sequence to structure and function / Sylvia B. Nagl -- Genes in population / François Cambien -- ...