The phosphatidylinositol-3-kinase (PI3K) pathway plays a crucial role in cell growth and survival and is activated in various cancers. Multiple components of the pathway are frequently targeted by ...

1 Primarily driven by an overactive PI3K pathway, early research suggests targeted ... Key interim findings include: Efficacy: Bimiralisib topical gel (2%) demonstrated strong efficacy with ...

Researchers from Tokyo University of Science uncover cellular and molecular mechanisms underlying the antidepressant-like effects of the delta opioid receptor agonists, paving the way for its ...