Myoclonus is a sudden and involuntary muscle spasm. It is usually a symptom of an underlying disorder and can interfere with eating, talking, and walking. The movement is involuntary and can’t be ...

What is Juvenile Myoclonic Epilepsy? Juvenile myoclonic epilepsy (JME) is an epileptic condition that develops in children and adolescents, invariably between the ages of 8 and 26 with most of the ...

Myoclonus is a sudden, random muscle jerk. It can happen alone or stem from a medical condition. Possible causes include medication side effects, damage to the nervous system, and disorders that ...

Loss-of-function mutations in the gene (CSTB) encoding human cystatin B, a widely expressed cysteine protease inhibitor, are responsible for a severe neurological disorder known as Unverricht-Lundborg ...

Gaucher disease, the inherited deficiency of lysosomal glucocerebrosidase, presents with a wide spectrum of manifestations. Although Gaucher disease has been divided into three clinical types, ...